The aim of this study was to determine the value of power Doppler sonograph
y in the detection of tumor vascularity in breast lesions and to find new d
iagnostic criteria for differential diagnosis. Power Doppler sonography was
prospectively performed in 102 patients with 118 histologic (n = 116) and
cytologic (n = 2) results. A semisubjective scoring system for the intratum
oral increase in blood flow compared with the flow in normal breast parench
yma (reference structure) was introduced and the flow pattern registered. T
he difference in the flow increase for benign and malignant breast disease
was highly significant (p less than or equal to 0.0001). This applied espec
ially to invasive cancer above a maximum tumor diameter of 5 mm excluding c
ancer stage Tis and Tla. A positive correlation be tween cancer size and fl
ow increase were found. The flow pattern was an additional feature. The sen
sitivity was calculated to be between 74.5 and 78.8 %, and the specificity
between 74.6 and 77.8 %. The level of flow increase in Power Doppler sonogr
aphy is an important feature in the differential diagnosis of breast lesion
s and should be considered together with the established criteria in B-mode
ultrasound. The flow pattern might also add some important information.