Cytotoxic T cells and mycobacteria

Authors
Silva, CL Bonato, VLD Lima, KM Coelho-Castelo, AAM Faccioli, LH Sartori, A De Souza, AO Leao, SC
Citation
Cl. Silva et al., Cytotoxic T cells and mycobacteria, FEMS MICROB, 197(1), 2001, pp. 11-18
Citations number
60
Categorie Soggetti
Microbiology
Journal title
FEMS MICROBIOLOGY LETTERS
ISSN journal
03781097 → ACNP
Volume
197
Issue
1
Year of publication
2001
Pages
11 - 18
Database
ISI
SICI code
0378-1097(20010401)197:1<11:CTCAM>2.0.ZU;2-W
Abstract
How the immune system kills Mycobacterium tuberculosis is still a puzzle. T he classical picture of killing due to phagocytosis by activated macrophage s may be only partly correct. Based on recent evidence, we express here the view that cytotoxic T lymphocytes also make an important contribution and suggest that DNA vaccines might be a good way to enhance this. (C) 2001 Fed eration of European Microbiological Societies. Published by Elsevier Scienc e B.V. All rights reserved.