A model of postsynaptic processes leading to a prolonged posttetanic m
odification (potentiation and depression) In the efficacy of the excit
atory and inhibitory Inputs to the neuron CA(3) of the hippocampus was
developed. The model enables one to estimate changes in postsynaptic
potentials depending on the extent of receptor phosphorylation, which
is determined by Ca2+-dependent changes in secondary messengers.