A MODEL FOR THE POSTTETANIC EFFICIENCY OF A NEURON DENDRITIC SPINE

Authors
MURZINA GB SILKIS IG
Citation
Gb. Murzina et Ig. Silkis, A MODEL FOR THE POSTTETANIC EFFICIENCY OF A NEURON DENDRITIC SPINE, Biofizika, 42(3), 1997, pp. 702-710
Citations number
35
Categorie Soggetti
Biophysics
Journal title
Biofizika → ACNP
ISSN journal
00063029
Volume
42
Issue
3
Year of publication
1997
Pages
702 - 710
Database
ISI
SICI code
0006-3029(1997)42:3<702:AMFTPE>2.0.ZU;2-R
Abstract
A model of postsynaptic processes leading to a prolonged posttetanic m odification (potentiation and depression) In the efficacy of the excit atory and inhibitory Inputs to the neuron CA(3) of the hippocampus was developed. The model enables one to estimate changes in postsynaptic potentials depending on the extent of receptor phosphorylation, which is determined by Ca2+-dependent changes in secondary messengers.