This paper addresses the layout configuration problem of workstations in a
unidirectional loop manufacturing system. In this popular unicyclic materia
l handling facility, the material transporters depart from the input/output
station, traverse each workstation exactly once, and then return to the in
put/output station. We show the important properties of this unidirectional
material handling loop network. Based on these characterizations, both heu
ristic and branch- and bound algorithms are proposed to solve such NP-compl
ete layout problems. Computational experiments with problem sizes up to 100
workstations are reported. Both the problem size and the material flow den
sity have been found to affect the solution quality and the computational e
fficiency. The proposed methods appear efficient and effective for solving
these layout problems.