This study used a computer-based rat anatomy to compare student learning ou
tcomes from computer-based instruction with a conventional dissection. The
study was carried out with first-year undergraduate biology students. On av
erage, students who completed the computer-based instruction did 7.4 percen
tage points better than students completing the conventional dissection. Th
is pattern held across the three types of questions, namely text, pictures,
and real rat questions. There was a significant relationship between the t
ime spent on both classes and the marks gained. Students who spent longer o
n the class gained higher marks and, regardless of time, the computer-based
students had higher marks. The increase in marks shown by the computer-bas
ed students was consistent across all grades of students. Possible reasons
for the increase in marks is the flexibility of time using the computer-bas
ed instruction, the ability to see all structures clearly and the absence o
f smell and blood. This study shows that computer-based instruction can be
a viable alternative to the use of animals in biology classrooms.