A simple method for aligning many protein sequences

Authors
Citation
P. Bladon, A simple method for aligning many protein sequences, J CHEM INF, 41(2), 2001, pp. 278-280
Citations number
12
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES
ISSN journal
00952338 → ACNP
Volume
41
Issue
2
Year of publication
2001
Pages
278 - 280
Database
ISI
SICI code
0095-2338(200103/04)41:2<278:ASMFAM>2.0.ZU;2-Q
Abstract
A simple extension of the Needleman and Wunsch algorithm for aligning pairs of protein sequences allows it to be used for the efficient generation of very large multiple-sequence alignments whose members are similar. This tec hnique could have applications in a broad range of high-volume genomics pro jects.