Persistent large choroid plexus cyst - A case report

BACKGROUND: Prenatally diagnosed choroid plexus cysts regress or resolve sp ontaneously during pregnancy. A persistent large choroid plexus cyst with a prenatal diagnosis has not been reported previously CASE: A 28-year-old, healthy primigravida was referred to our department at 32 weeks' gestation for a suspected fetal intracranial anomaly. Ultrasonog raphy revealed a lateral ventricle 13 mm in width. The ventricle was dilate d only in the atrium region. The choroid plexus was not distinct from the i nner wall of the ventricle and did not fill the atrium of the lateral ventr icle. The patient was followed with biweekly ultrasonography until delivery , and the left ventricular width increased from 13 to 17 mm. At 38 weeks' g estation the patient delivered a 3,350-g girl. Magnetic resonance imaging s howed a 1.7x2.5x3.0-cm cyst in the left lateral ventricle. Follow-up magnet ic resonance imaging scans at 6 and 11 months showed unchanged findings. Cl inical and neurologic examinations at 11 months of age showed normal develo pment. CONCLUSION: Although small (<1 cm), postnatally persistent choroid plexus c ysts are clinically insignificant variants of normal; the prognosis of larg e, persistent cysts (<greater than or equal to>1 cm) is less clear. Long-te rm neurologic follow-up is mandatory for these neonates.