Objectives: Acquired upper airway stenosis is usually associated with a com
plex of pathological conditions at the high tracheal and the subglottic lev
els. Reported reconstructive techniques include widening by incorporation o
f grafts, segmental resection, and anastomosis or combined procedures. The
management of recurrent stenosis after reconstructive surgery is a major ch
allenge and has rarely been discussed in the literature. The purposes of th
e present study are to compare the clinical course of primary versus revise
d reconstructive procedures and to analyze the effect of age, diabetes, chr
onic lung disease, grading of stenosis, extent of resection, and revised pr
ocedures on the operative rate of success. Study Design: A cohort study in
a tertiary referral medical center. Methods: The clinical course of 23 cons
ecutive patients undergoing laryngotracheal anastomosis was studied compari
ng a group of 13 primary with 10 revision procedures. Seventeen patients un
derwent cricotracheal and six patients thyrotracheal anastomoses. Ad patien
ts but one were tracheotomized before the definitive reconstructive procedu
re. Supra-hyoid release was routinely performed except for two cases, and o
nly one patient required sternotomy. The Wilcoxon test was used to examine
the relationship between preoperative clinical parameters and the postopera
tive success (i.e., airway patency). Results: Twenty-two of 23 patients (95
.6%) had successful decannulation. Four patients required a revision proced
ure because of repeat stenosis at the site of the anastomosis (2) or distal
tracheal malacia (2). Residual airway stenosis of less than 50% was noted
in six patients, although only three complained of dyspnea during daily-act
ivity exertion. There was no associated mortality. Complications included s
ubcutaneous emphysema (4), granulation tissue formation (3), pneumonia (2),
cardiac arrhythmia (2), and one each of pneumomediastinum, neck hematoma,
and urosepsis. Protracted aspirations were noted in one patient who had rev
ision surgery. Age wits the only parameter that correlated nit h postoperat
ive airway patency (P <.07), whereas the presence of chronic obstructive lu
ng disease and diabetes, grade of stenosis, type of surgery, and revision s
urgery were found to be insignificant. Conclusions: The clinical course of
laryngotracheal anastomosis in primary and revised procedures was similar i
n our group of patients. The operation can be performed safety with an expe
cted high rate of success and acceptable morbidity.