In a patient with a defibrillator system incorporating a lead with integrat
ed bipolar sensing, physical contact between a guidewire (inserted for veno
us access) and the right ventricular defibrillation coil created sensing ar
tefacts that triggered an inappropriate discharge. The presence of the guid
ewire in the heart during the discharge resulted in an electrical short wit
h irreversible damage to the generator and rendered it incapable of deliver
ing further high voltage therapy.