Elongation of the aorta and multiple cardiovascular abnormalities associated with Larsen syndrome

Larsen syndrome is a genetically heterogeneous group of disorders character ized by multiple joint dislocations and a characteristic face. We describe a girl with the typical features of Larsen syndrome. She also had associate d multiple cardiovascular anomalies. The anomalies included elongation of t he aorta, bicuspid aortic valve, subaortic stenosis, mitral valve prolapse with mitral regurgitation, atrial septal defect of the secundum type, and a patent ductus arteriosus.