Successful treatment of visceral leishmaniasis with allopurinol plus ketoconazole in an infant who developed pancreatitis caused by meglumine antimoniate

Pentavalent antimony is still the drug of choice in the treatment of viscer al leishmaniasis. Pantavalent antimony can cause a wide range of adverse ef fects, the most serious of which are cardiotoxicity and hepatotoxicity. Acu te pancreatitis is a rarely reported adverse effect. An infant who develope d pancreatitis during meglumine antimoniate treatment for visceral leishman iasis and who was successfully treated with a combination of allopurinol an d ketoconazole is reported.