Determination of bronopol in cosmetic products by HPLC with electrochemical detection

Authors
Scalia, S Simeoni, S Bousquet, E
Citation
S. Scalia et al., Determination of bronopol in cosmetic products by HPLC with electrochemical detection, PHARMAZIE, 56(4), 2001, pp. 318-320
Citations number
13
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PHARMAZIE
ISSN journal
00317144 → ACNP
Volume
56
Issue
4
Year of publication
2001
Pages
318 - 320
Database
ISI
SICI code
0031-7144(200104)56:4<318:DOBICP>2.0.ZU;2-O
Abstract
A procedure is described for the assay of bronopol in cosmetics by HPLC cou pled with constant-potential amperometric detection. Samples were analysed on an Alltima C-18 column with methanol-phosphate buffer as the eluent and detected at a porous graphite electrode set at a reduction potential of -0. 9 V. The recovery of bronopol from different cosmetic matrices was between 96.4 and 98.8% and the precision of the method was better than 4.5% relativ e standard deviation.