Ketoprofene gel-induced allergy

A common observation: Ketoprofene gels, widely used to treat benign conditi ons, can provoke local intolerance. The most commonly reported clinical fea tures include eczema, sometimes severe acute contact photoallergy that ofte n spread beyond the site of application and may even lead to a long-duratio n generalized reaction. Diagnosis: Photoallergological tests allow positive diagnosis of the ketopr ofene-induced contact photosensitization and underline the role of the benz ophenone ring, explaining certain cross allergies with fenofibrate and oxyb enzone. Precautions for use: The primary rule is to avoid sun exposure, requiring b etter information for prescribers and patients.