Eyk. Ng et Nm. Sudharsan, An improved three-dimensional direct numerical modelling and thermal analysis of a female breast with tumour, P I MEC E H, 215(H1), 2001, pp. 25-37
Citations number
32
Categorie Soggetti
Mechanical Engineering
Journal title
PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE
It is well known that malignant tumour tissue generally has higher metaboli
c and blood perfusion rates than most normal tissues. The authors aim to sh
ow that the tissue temperature profile within the breast and the surface te
mperature profile can be quantified to develop an expert system or diagnost
ic tool for boast cancer detection. The surface temperature and tissue temp
erature profiles are analysed for a three-dimensional numerical model of a
normal breast and a breast with a tumour. Tumours of different sizes are pl
aced at various locations. In the model, the tissue temperature profile is
distorted at the tumour location and was found to compare well with in vivo
tests. It was also found that as the tumour was moved to deeper locations
its effect on surface temperature was lower. It was observed that small tum
ours in deeper regions do not have a significant isolated impact on the sur
face. The numerical results could also capture a shift in the position of t
he tumour. For tumours greater than 10 mm in the superficial regions and of
significant size in deeper regions, it could be seen that the surface temp
erature distribution of the breast is directly related to the position and
size of the tumour embedded in it. The feasibility of providing a diagnosti
c tool in conjunction with numerical modelling and high-resolution thermogr
ams is also discussed.