Background: Patients with chronic heart failure have a lower inspiratory mu
scle strength and fatigue endurance. Aim: To assess the effects of selectiv
e training of respiratory muscles in patients with heart failure. Patients
and methods: Twenty patients with stable chronic heart failure, aged 58.3+/
-3 years with an ejection fraction of 28+/-9%, were subjected to respirator
y muscle training with threshold valves. The load was fixed in 30% of maxim
al inspiratory pressure (PImax) in 11 and in 10% of PImax in nine. Two sess
ions of 15 minutes, 6 days per week, during 6 weeks were done. Degree of dy
spnea (Mabler score), maximal oxygen uptake, distance walked in 6 minutes,
respiratory muscle function and left ventricular ejection fraction were mea
sured before and after training. Results: Both training loads were associat
ed to an improvement in dyspnea (+2.7+/-1.8 and +2.8+/-1.8 score points wit
h 30% PImax and 10% PImax respectively), maximal oxygen uptake (from 19+/-3
to 21.6+/-5 and from 16+/-5 to 18.6+/-7 ml/kg/min with 30% PImax and 10% P
Imax respectively, p<0.05, PImax (from 78+/-22 to 99+/-22 and from 72+/-34
to 82.3 cm H2O with 30% PImax and 10% PImax respectively), sustained PImax
(from 63+/-18 to 90+/-22 and from 58+/-3 to 69+/-3 cm H2) with 30% PImax an
d 10% PImax respectively), and maximal sustained load (from 120+/-67 to 195
+/-47 and from 139+/-120 to 192+/-154 g with 30% PImax and 10% PImax respec
tively). The distance walked in 6 min only increased in subjects trained at
30% PImax (from 451+/-78 to 486+/-68 m). Conclusions: Selective training o
f respiratory muscles results in a functional improvement of patients with
chronic heart failure.