Gram scale-up synthesis of all-(Z)-cyclododecatetraene: A comparison between intramolecular Wittig and ring closing metathesis approaches

Authors
Guiard, S Santelli, M Parrain, JL
Citation
S. Guiard et al., Gram scale-up synthesis of all-(Z)-cyclododecatetraene: A comparison between intramolecular Wittig and ring closing metathesis approaches, SYNLETT, (4), 2001, pp. 553-556
Citations number
17
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
4
Year of publication
2001
Pages
553 - 556
Database
ISI
SICI code
0936-5214(200104):4<553:GSSOAA>2.0.ZU;2-5
Abstract
A total synthesis of all-(Z)-cyclododeca-1,4,7,10-tetraene was achieved in 28% overall yield using an intramolecular Wittig reaction as key step while an approach based on ring closing metathesis was found ineffective.