Dealkylation of dialkyl phosphonates with boron tribromide

Authors
Gauvry, N Mortier, J
Citation
N. Gauvry et J. Mortier, Dealkylation of dialkyl phosphonates with boron tribromide, SYNTHESIS-S, (4), 2001, pp. 553-554
Citations number
21
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
4
Year of publication
2001
Pages
553 - 554
Database
ISI
SICI code
0039-7881(200104):4<553:DODPWB>2.0.ZU;2-W
Abstract
Boron tribromide cleanly and quantitatively converts dimethyl-, diethyl-, d iisopropyl-, and ditertiobutyl phosphonates RP(O)(OR')(2) into the correspo nding phosphonic acids RP(O)(OH)(2) via methanolysis. The use of boron trib romide is compatible with a variety of functionalities in the R group.