New cytochalasans, penochalasins D-H, have been isolated along with chaetog
lobosin O from a strain of Penicillium sp. originally separated from the ma
rine al,oa Enteromorpha intestinalis, and their stereostructures have been
established on the basis of spectral analyses. AU the compounds exhibited s
ignificant cytotoxicity against cultured P388 cells. (C) 2001 Elsevier Scie
nce Ltd. All rights reserved.