One-pot inter- and intramolecular Friedel-Crafts reactions in Baylis-Hillman chemistry: a novel facile synthesis of (E)-2-arylideneindan-1-ones

Citation
D. Basavaiah et Rm. Reddy, One-pot inter- and intramolecular Friedel-Crafts reactions in Baylis-Hillman chemistry: a novel facile synthesis of (E)-2-arylideneindan-1-ones, TETRAHEDR L, 42(16), 2001, pp. 3025-3027
Citations number
24
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
16
Year of publication
2001
Pages
3025 - 3027
Database
ISI
SICI code
0040-4039(20010416)42:16<3025:OIAIFR>2.0.ZU;2-Z
Abstract
A simple one-pot stereoselective transformation of tert-butyl 3-aryl-3-hydr oxy-2-methylenepropanoates, the Baylis-Hillman adducts obtained from t-buty l acrylate, into (E)-2-arylideneindan-1-ones involving one inter- and one i ntramolecular Friedel-Crafts reaction is described. (C) 2001 Elsevier Scien ce Ltd. All rights reserved.