A di-O-dihydrogeranylgeranyl glycerol from Thermococus S 557, a novel ether lipid, and likely intermediate in the biosynthesis of diethers in Archaea

Authors
Gonthier, I Rager, MN Metzger, P Guezennec, J Largeau, C
Citation
I. Gonthier et al., A di-O-dihydrogeranylgeranyl glycerol from Thermococus S 557, a novel ether lipid, and likely intermediate in the biosynthesis of diethers in Archaea, TETRAHEDR L, 42(15), 2001, pp. 2795-2797
Citations number
20
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
15
Year of publication
2001
Pages
2795 - 2797
Database
ISI
SICI code
0040-4039(20010409)42:15<2795:ADGFTS>2.0.ZU;2-K
Abstract
The lipids of a deep-sea hydrothermal vent arch ae on, Thermococcus S 557, were isolated, purified and structurally determined. Based on acid methanol ysis and spectroscopic studies, the polar lipids were shown to comprise dip hytanyl glycerol and dibiphytanyl diglycerol, typical membrane lipids of Ar ch aea. From the neutral lipids, 2,3-di-O-dihydro-14,15-geranylgeranyl glyc erol was isolated. This novel ether lipid is, very likely, a close intermed iate in the biosynthesis of diphytanyl glycerol diether in Arch aea. (C) 20 01 Elsevier Science Ltd. All rights reserved.