Nucleophilic reactions of propargyl acetates mediated by titanocene dichloride and magnesium

Authors
Yang, FL Zhao, G Ding, Y
Citation
Fl. Yang et al., Nucleophilic reactions of propargyl acetates mediated by titanocene dichloride and magnesium, TETRAHEDR L, 42(15), 2001, pp. 2839-2841
Citations number
5
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
15
Year of publication
2001
Pages
2839 - 2841
Database
ISI
SICI code
0040-4039(20010409)42:15<2839:NROPAM>2.0.ZU;2-E
Abstract
Reaction of Cp2TiCL2/Mg with propargyl acetates form allenyl titanium inter mediates, which undergo nucleophilic addition reactions to aldehydes or ket ones to give homopropargyl alcohols in high yields. Subsequent nucleophilic addition to acetonitrile and nucleophilic substitution with allyl bromide are also mentioned. (C) 2001 Elsevier Science Ltd. All rights reserved.