Asymmetric cyclopropanation of styrene with ethyl diazoacetate using a N2P2-ligand ruthenium(II) catalyst: axial ligand controlled enantioselectivity

Authors
Zheng, Z Yao, XQ Li, C Chen, HL Hu, XQ
Citation
Z. Zheng et al., Asymmetric cyclopropanation of styrene with ethyl diazoacetate using a N2P2-ligand ruthenium(II) catalyst: axial ligand controlled enantioselectivity, TETRAHEDR L, 42(15), 2001, pp. 2847-2849
Citations number
28
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
15
Year of publication
2001
Pages
2847 - 2849
Database
ISI
SICI code
0040-4039(20010409)42:15<2847:ACOSWE>2.0.ZU;2-R
Abstract
The N2P2-Ru(II) complex 1, activated by silver triflate, exhibited good cat alytic activity but low enantioselectivity in the asymmetric cyclopropanati on of styrene with ethyl diazoacetate. N-Donor additives were introduced in to the activated system as axial ligands to improve the ee's for this react ion. Up to 90% ee for cis-isomers was achieved by using 2,4,6-collidine as an additive. (C) 2001 Elsevier Science Ltd. All rights reserved.