Primary genitourinary melanoma

Objectives. To describe the presentation, management, and clinical outcome of patients with genitourinary melanoma. Methods. We identified 14 patients with genitourinary melanoma treated at M emorial Sloan-Kettering Cancer Center, New York and Tripler Army Medical Ce nter, Honolulu, Hawaii. The presentation, surgical treatment, disease progr ession, and outcome of these patients were reviewed. Survival was analyzed, using the Kaplan-Meier product limit method. Results. The presentation and management of patients with genitourinary mel anoma were varied. Overall, the prognosis was poor, with a median survival of 43 months, and only 3 patients were alive, without disease, at last foll ow-up. Our findings confirm a poor prognosis in patients with this rare dis ease. Conclusions. Genitourinary melanoma is a rare form of the disease with an u nfavorable clinical outcome. Less than one third of patients survive long t erm, although patients with scrotal melanomas may have a better prognosis. UROLOGY 57: 633-638, 2001. (C) 2001, Elsevier Science Inc.