Background and Objectives Considering the clinical importance of blood tran
sfusions, the limited knowledge of transfusion practices is remarkable. New
methods are needed to elucidate the observed variation of transfusion prac
tices.
Materials and methods All patients transfused or pretransfusion tested (i.e
. at risk for blood transfusion) at two tertiary teaching hospitals during
the full years of 1997 and 1998 were included in the study.
Results The observed practices contained substantial variance at the level
of hospitals. The contributions to the total variance of the different spec
ialities were highly significant, as was the contribution of hospitals to t
he variance in plasma and platelet transfusions. Significant interactions b
etween hospitals and specialities were observed in transfusion of red cells
, plasma and platelets.
Conclusion To our knowledge this is the first survey of this size to combin
e transfusions, diagnoses and biochemical tests, exclusively based on an ex
isting computerized register. The aim is to establish a basis for compariso
n of local transfusion practices with other commensurate hospitals and regi
ons at a national (and international) level.