Va. Chandiramani et al., HOW TO RECOGNIZE PATIENTS WITH PARKINSONISM WHO SHOULD NOT HAVE UROLOGICAL SURGERY, British Journal of Urology, 80(1), 1997, pp. 100-104
Objective To examine whether there are urogenital criteria that the ur
ologist could apply to a patient with idiopathic Parkinson's disease (
IPD) and bladder symptoms, and so avoid operating on patients with mul
tiple system atrophy (MSA). Patients and methods The clinical features
of 52 patients with probable MSA and 41 patients with TPD were studie
d retrospectively with particular attention to the nature of lower uri
nary tract symptoms and erectile dysfunction in relation to the onset
of parkinsonism. Anal sphincter electromyography (EMG) was recorded in
all the patients with MSA and in 12 of the patients with IPD. Results
Of the patients with MSA, 60% had urinary symptoms preceding or prese
nting with IPD but in 94% of the patients with IPD the neurological di
agnosis preceded the onset of urogenital symptoms. Most of the patient
s with MSA (73%) had troublesome urinary incontinence whereas the majo
rity of those with IPD (85%) had urgency and frequency but were not in
continent; 66% of the patients with MSA and 16% of patients with TPD h
ad a significant post-void residual volume. Of the men with MSA, 93% h
ad erectile dysfunction and in 48% of them this complaint preceded the
diagnosis of MSA. All 11 men with MSA who had a TURF were incontinent
post-operatively. Conclusion The urogenital criteria which favour a d
iagnosis of MSA are: (i) urinary symptoms preceding or presenting with
parkinsonism; (ii) urinary incontinence and IPD; (iii) a significant
post-void residual urine volume; (iv) erectile failure preceding or pr
esenting with parkinsonism; and (v) worsening bladder control after ur
ological surgery, Patients with parkinsonism and these features should
be offered medical management rather than urological surgery.