Colonoscopy and polypectomy effectively reduce the incidence and mortality
of colorectal cancer, but some patients present with fully developed cancer
s within 1-4 yr of a colonoscopy that apparently cleared the colon of neopl
asia. These events may result in medical-legal action against colonoscopist
s, generally based on an assumption of negligent technical performance of t
he procedure. Alternative explanations for the development of interval canc
ers include variable growth rates of colorectal cancers, the inherent miss
rate of the procedure even when optimal examination techniques are used, an
d the possibility of flat lesions that are not readily detected by standard
colonoscopic techniques. This paper discusses issues relevant to reduction
of medical-legal risks associated with interval cancers after clearing col
onoscopy. These issues include informed consent, documentation of cecal int
ubation, appropriate description of preparation, documentation of examinati
on time and technique, and attention to potential atypical neoplasms. (Am J
Gastroenterol 2001.96:952-957. (C) 2001 by Am. Cell. of Gastroenterology).