Massive progression of diffuse hepatic lymphangiomatosis after liver resection and rapid deterioration after liver transplantation

Hepatic involvement is an exceptional presentation of lymphangiomatosis. In this case report we describe a patient who underwent liver transplantation secondary to progressive hepatic involvement, which occurred 2 yr after pa rtial hepatectomy. Within 1 yr after liver transplantation the disease cond ition deteriorated, with rapid progression of pre-existing skeletal lesions and development of pulmonary disease. We conclude that liver transplantati on may be a treatment option for hepatic lymphangiomatosis. In the presence of pre-existing extrahepatic lesions, however, liver transplantation seems to be contraindicated. (Am J Gastroenterol 2001;96:1278-1281. (C) 2001 by Am. Coll. of Gastroenterology).