T2 relaxation measurements in X-linked adrenoleukodystrophy performed using dual-echo fast fluid-attenuated inversion recovery MR imaging

The purpose of this study was to determine whether dual-echo fast fluid-att enuated inversion recovery MR imaging and corresponding T2 brain maps can s how different zones in the affected white matter of patients with cerebral X-linked adrenoleukodystrophy. Ten male patients with cerebral X-linked adr enoleukodystrophy underwent imaging performed using dual-echo fast fluid-at tenuated inversion recovery and dual-echo conventional spin-echo MR sequenc es. Corresponding T2 relaxation maps of the brain were generated. On the ba sis of dual-echo fast hold-attenuated inversion recovery images and T2 maps , the affected white matter could be divided into two distinct zones in fou r patients with cerebral X-linked adrenoleukodystrophy.