Tyrosinases from various organisms are compared with respect to enzyma
tic structure, primary, secondary and tertiary structure, domain struc
ture, Cu binding sites, maturation mechanism and activation mechanism.
On the basis of these comparisons, and by using hemocyanin structure
as a template, a structure model for the active site of tyrosinases is
proposed. (C) 1997 Elsevier Science Ltd. All rights reserved.