7,8-dihydropterin-6-carboxylic acid as light emitter of luminous millipede, Luminodesmus sequoiae

Authors
Kuse, M Kanakubo, A Suwan, S Koga, K Isobe, M Shimomura, O
Citation
M. Kuse et al., 7,8-dihydropterin-6-carboxylic acid as light emitter of luminous millipede, Luminodesmus sequoiae, BIOORG MED, 11(8), 2001, pp. 1037-1040
Citations number
9
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
11
Issue
8
Year of publication
2001
Pages
1037 - 1040
Database
ISI
SICI code
0960-894X(20010423)11:8<1037:7AALEO>2.0.ZU;2-5
Abstract
A luminous millipede, Luminodesmus sequoiae, emits light centered at a wave length of 500 nm. To determine the light emitter of this bioluminescent sys tem. fluorescent compounds were isolated from pulverized cuticles. NMR and MS spectra of these compounds showed them to be pterin derivatives. Further more, proton/deuterium (HD) exchange experiments by ESI-Q-TOF-MS and -MS/MS measurements have proved to be a powerful tool for elucidating these heter oaromatic compounds. Finally? we have concluded that 7,8-dihydropterin-6-ca rboxylic acid. a new natural product. is the light emitter of Liminodesrmus bioluminescence. (C) 2001 Elsevier Science Ltd. All rights reserved.