Modified coumarins. II. Mannich reaction of substituted 4-phenylcoumarins

Authors
Garazd, MM Garazd, YL Shilin, SV Khilya, VP
Citation
Mm. Garazd et al., Modified coumarins. II. Mannich reaction of substituted 4-phenylcoumarins, CHEM NAT CO, 36(5), 2000, pp. 485-492
Citations number
7
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
CHEMISTRY OF NATURAL COMPOUNDS
ISSN journal
00093130 → ACNP
Volume
36
Issue
5
Year of publication
2000
Pages
485 - 492
Database
ISI
SICI code
0009-3130(200009/10)36:5<485:MCIMRO>2.0.ZU;2-#
Abstract
Aminomethylation of 5-hydroxy- and 7-hydroxy-4-phenylcoumarins by substitut ed 1, 1-dianzinomethanes is studied Mannich condensation of amino acids and their esters with 7-hydroxy-4-phenylcoumarin gives a series of 8-aminoacyl methylcoumarins and 4-phenyl-9, 10-dihydro-2H, 8H-chromeno[8, 7-e][1, 3]oxa zin-2-ones.