Laparoscopic surgery of the upper gastrointestinal tract is nowadays associ
ated with little morbidity and mortality. Cardiomyotomy with semifundoplica
tion for management of achalasia and the various forms of fundoplication fo
r treatment of reflux syndrome have proved beneficial and have largely repl
aced conventional surgery. Independent of the operative approach, it has no
t yet been established with certainty whether gastro-esophageal reflux can
best be prevented by 360 degrees fundoplication or semifundoplication. A pe
rforated peptic ulcer can be treated effectively by laparoscopic over-stitc
hing of omental patch-plasty, although the superiority of the laparoscopic
method has yet to be proved. Benign lesions and early malignancies are curr
ently resected laparoscopically, but the role of laparoscopy in the curativ
e treatment of advanced gastric carcinoma remains to be clarified. Diagnost
ic laparoscopy is used to avoid unnecessary laparotomy in inoperable cancer
and to ascertain whether neoadjuvant therapy is indicated in advanced gast
ric carcinoma.