Over the recent years laparoscopic splenectomy has become the preferred app
roach for the treatment of many conditions requiring splenic removal. At fi
rst limited to small spleens and to benign hematologic disorders, this proc
edure is now used for a variety of indications. Enlarged spleens are possib
le to be removed laparoscopically, although this is still a demanding proce
dure. Two factors facilitated the technique and contributed to its wide acc
eptance: 1) Change in the technique originally used, by positioning the pat
ient in right lateral decubitus, and approaching the spleen from a postero-
lateral direction. 2) The development of new technologies to dissect and di
vide tissues and vessels, including the ultrasonic shears and the laparosco
pic linear stapler. In this article we review the current indications for l
aparoscopic splenectomy, as well as the techniques to accomplish this proce
dure.