The first three cases of acute human granulocytic ehrlichiosis in Poland ar
e described. Blood samples were tested by an indirect immunofluorescence me
thod to detect specific serum antibodies, and the polymerase chain reaction
was used to detect ehrlichial DNA. Additionally, peripheral blood smears w
ere examined for the presence of morulae. According to criteria of the Cent
ers for Disease Control and Prevention, all three cases can be classified a
s confirmed granulocytic ehrlichiosis. Using the criteria recommended by a
consensus group, however, two cases can be classified as confirmed granuloc
ytic ehrlichiosis and one case as probable granulocytic ehrlichiosis.