Objective: To define the incidence of a distinct tubercle of Zuckerkandl (T
Z) and confirm its anatomical relationships with the recurrent laryngeal ne
rve and the superior parathyroid gland.
Design: Two prospective series.
Setting: University teaching hospital, Australia.
Subjects: 200 patients who required thyroidectomy.
Interventions: Anatomical and clinical observations in two series of patien
ts (n = 100 in each). The first defined the incidence of a TZ and preoperat
ive symptoms; the second delineated the relationship of the TZ to the recur
rent laryngeal nerve and the superior parathyroid gland.
Main outcome measures: Anatomical relationships.
Results: A TZ was identified in 63% of patients and was >1 cm in 45%. In 93
% of patients with an enlarged TZ, the recurrent laryngeal nerve lay medial
to it and the nerve was found lateral to the TZ in 7% of cases. The superi
or parathyroid gland was usually cranial to the TZ and posterior to the rec
urrent laryngeal nerve. The size and position of the TZ did not correlate c
learly with symptoms.
Conclusions: The TZ is a distinct feature of the thyroid gland that can be
recognised during most thyroidectomies. The size and the position of the TZ
have no constant relationship to preoperative symptoms. An understanding o
f the consistent anatomical relationship between the TZ and recurrent laryn
geal nerve and superior parathyroid gland is crucial for safe thyroidectomy
.