Objectives: since cuff dimensions are variable, we studied the influence of
cuff geometry on flow mechanics, in an attempt to identify the optimum con
figuration.
Materials and methods: bench studies involved the manufacture of anatomical
ly accurate models of varying cuff dimensions, perfused in a specifically d
esigned flow rig, simulating physiological conditions. Flow visualisation s
tudies incorporating laser illumination of tracer particles enabled accurat
e analysis of flow patterns.
Results: the vortex created within the proximal cuff of each model during t
he decleration phase of the cardiac cycle was strongly influenced by the as
pect ratio (AR = cuff height:length). The standard and high cuffs (AR = 1.6
3 and 1.18, respectively) demonstrated cohesive vortices and stable flow pa
tterns. Low and long cuffs (AR = 2.6 and 2.25, respectively) created more c
omplex vortices with large areas of flow separation and low velocities.
Conclusions: aspect ratio has an important influence on flow within the dis
tal anastomosis, with cuff dimensions of 13 mm long and 8-11 mm high (stand
ard and high cuffs) creating beneficial flow patterns anticipated to optimi
se wall shear stress and inhibit myointimal hyperplasia.