Sa. Hull et al., Prescribing rates for psychotropic medication amongst east London general practices: low rates where Asian populations are greatest, FAM PRACT, 18(2), 2001, pp. 167-173
Objectives. The aim of this study was to examine the contribution of Asian
ethnicity to the variation in rates of practice prescribing for antidepress
ant and anxiolytic medication, taking into account other population and pra
ctice organizational factors.
Methods. A practice-based cross-sectional survey was carried out of the pre
scribing of antidepressants and anxiolytics (daily defined dosages) in 164
general practices. The study was set in East London and the City Health Aut
hority, which includes the multiethnic inner London boroughs of Hackney, To
wer Hamlets, Newham and the City of London. The main outcome measures were
the annual prescribing rates for each group of drugs, calculated as the tot
al annual daily defined dosages divided by the practice population, and the
ratio of antidepressant/anxiolytic annual prescribing rates.
Results. Prescribing rates for antidepressants showed a 25-fold variation b
etween practices; this was greater for anxiolytics. The median annual presc
ribing rate for all antidepressants combined was 4.13 (interquartile range
2.50-5.88). For all anxiolytics and hypnotics combined the median annual pr
escribing rate was 3.55 (interquartile range 1.71-6.36). Univariate analysi
s showed that Asian ethnicity alone accounted for 28% of the variation in a
ntidepressant prescribing and 20.5% of the variation in the anxiolytic pres
cribing. A backwards multiple regression model using 10 explanatory practic
e and population variables accounted for 47.7% of the variance in antidepre
ssant prescribing and 34% of the variance in the anxiolytic prescribing.
Conclusion. In practices where the proportion of Asian patients is high, bo
th antidepressant and anxiolytic prescribing is low. This is important for
understanding interpractice prescribing variation and for setting levels of
drug budgets. This study confirms that the low rates of non-psychotic diso
rders presented by Asian populations is not a selective feature of access t
o secondary care, but is evident in the prescribing behaviour of GPs. Uncer
tainty remains as to how much this is due to a lower prevalence rate, 'cult
ure-bound syndromes' or practical difficulties in diagnosis and management
within the general practice setting.