The incidence of occupational dermatitis of the hands is particularly high
in the hairdressing trade. To elucidate the role of various risk factors, a
nd to ultimately improve primary prevention of occupational hand dermatitis
, a prospective cohort study was conducted between 1992 and 1997, including
2352 hairdressing trainees. Already six weeks after the start of training
(median) 35.4% had - usually mild - irritant skin changes, mainly involving
the interdigital web spaces. These were associated with subsequent, possib
ly more severe, hand dermatitis. Reduced exposure to wet work, i.e., improv
ed skin protection with gloves, often led to the resolution of dermatitis o
f the hands. In conclusion, early irritant skin damage is a sentinel event
that heralds possibly disabling occupational skin disease and should prompt
adequate preventive measures.