This retrospective study of risk factors for testicular atrophy in HIV-infe
cted men investigates the relationship between complications of AIDS such a
s wasting or opportunistic illness and testicular atrophy. Microscopic sect
ions of the right testis were evaluated for testicular atrophy by assessing
the mean score in each of 80 selected HIV-infected patients who underwent
an autopsy during a one-year period. A significant association was observed
between testicular atrophy and body mass index (BMI) (P=0.0496). Thus, und
erweight patients with HIV infection were 3.52 times more likely to have te
sticular atrophy than those with acceptable body weight. Other significant
associations between other variables were not found.