Purpose: The Swedish Interactive Thresholding Algorithm (SITA) is a new tes
ting strategy for the Humphrey perimeter. The standard SITA algorithm short
ens test time in adults without increasing variability, but its usefulness
for detecting field defects in children has not been investigated. Methods:
We evaluated 92 standard SITA 24-2 visual fields of children, most of whom
had various types of optic neuropathies (pediatric idiopathic intracranial
hypertension, homonymous defects, bitemporal defects, papilledema from bra
in tumors), and compared them with 49 full threshold 24-2 fields obtained i
n similar patients. We evaluated outcome measures of foveal threshold, mean
defect, pattern standard deviation, false-negative and false-positive rate
s, and test time. Five children (9 eyes) had both SITA and full threshold t
esting (FTT). Results: The SITA decreased test time by over 50% compared wi
th FTT (12.6 +/- 3.0 minutes vs 6.6 +/- 1.6 minutes [P <.00001]). When pati
ents with field defects were eliminated, the pattern standard deviation was
lower with SITA than FTT (P <.002), indicating lower intratest variability
of SITA in subjects with normal fields. No detectable difference was obser
ved in the other outcome measures. Subjective analysis of gray-scale fields
in patients who underwent testing with the use of both strategies showed m
arked similarities. Conclusions: SITA shortens test time significantly comp
ared with FTT and does so without jeopardizing interpretability. SITA has l
ess intratest variability than RT and therefore should be better for detect
ing and following defects. Caution is advised when following a visual field
defect unless the same strategy is used for each evaluation. Switching str
ategies in the absence of a stable field defect is not recommended.