The aim of this prospective study was to examine the severity and character
of somatic comorbidity when addicted patients were admitted to hospital fo
r detoxification. The study was conducted at a university-based psychiatric
clinic. Somatic comorbidity was registered by laboratory, radiological and
electrocardiographic parameters and by the amount of non-psychiatric consu
ltations. Besides the number of patients with dual diagnosis interpreted as
combination of addictive and psychiatric diseases was registered. A total
of 111 consecutive patients (32 women) was divided into patients with alcoh
ol dependence and patients with other addictive diseases including polydrug
abuse and opiate dependence. Patients with alcohol dependence were charact
erized by an elevated heart rate and higher values for gamma -glutamyltrans
ferase. Nu significant differences between groups could be found for the ra
te corrected QT interval and cardiothoracic ratio. Although viral liver dis
ease was diagnosed in both groups patients with a history of injecting drug
use were at greatest risk for hepatitis C. About one-third of all patients
required consultant nan-psychiatric treatment. Concomitant heart and pulmo
nary diseases were mole pronounced in tile alcohol dependence group. The fi
ndings emphasize that hospitalization of addicted patients yields relevant
somatic morbidity which has an impact on cost and requires medically superv
ised detoxification programs. (C) 2001 by The Haworth Press, Inc. All right
s reserved.