Carcinoma of the cystic duct associated with pancreaticobiliary maljunction

We report a rare case of carcinoma of the cystic duct (CCD) associated with pancreaticobiliary maljunction (PBM). A 63-year-old man had presented with relapsing cholecystitis of 4 months, duration, Computed tomography showed a distended gallbladder: however, a small mass in the cystic duct was overl ooked. Endoscopic retrograde cholangiopancreatography demonstrated a long c ommon channel (20-mm-long) and fusiform dilatation of the common bile duct, findings which were consistent with PBM. At laparotomy, we found a papilla ry tumor,:20 mm in diameter, that obstructed the cystic duct. The patient u nderwent resection of the gallbladder and the common bile duct, lymph node dissection in the hepatoduodenal ligament, and hepaticojejunostomy. Histolo gic study revealed a papillary adenocarcinoma confined within the subserosa l space, There was no lymphatic or perineural invasion of cancer cells. The surrounding cystic ductal mucosa showed dysplasia and hyperplasia, and the gallbladder and common bile duct showed severe inflammation. The patient h as been doing well for 16 months after surgery. without tumor recurrence. T his case suggests a relationship between CCD and chronic biliary inflammati on caused by PBM, as in cases of gallbladder carcinoma.