Quantitative magnetic resonance imaging in traumatic brain injury

Quantitative neuroimaging has now become a well-established method for anal yzing magnetic resonance imaging in traumatic brain injury (TBI). A general review of studies that have examined quantitative changes following TBI is presented. The consensus of quantitative neuroimaging studies is that most brain structures demonstrate changes in volume or surface area after injur y. The patterns of atrophy are consistent with the generalized nature of br ain injury and diffuse axonal injury. Various clinical caveats are provided including how quantitative neuroimaging findings can be used clinically an d in predicting rehabilitation outcome. The future of quantitative neuroima ging also is discussed.