I construct a map from the Grothendieck group of coherent sheaves to K-homo
logy. This results in explicit realizations of K-homology cycles associated
with D-brane configurations. Non-abelian degrees of freedom arise in this
framework from the deformation quantization of N-tuple cycles. The large-N
limit of the gauge theory on D-branes wrapped on a subvariety V of some var
iety X is geometrically interpreted as the deformation quantization of the
formal completion of X along V.