Simplified synthesis of oligoethylene glycols

Authors
Zada, A Avny, Y Zilkha, A
Citation
A. Zada et al., Simplified synthesis of oligoethylene glycols, J SURFACT D, 4(2), 2001, pp. 163-166
Citations number
18
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
JOURNAL OF SURFACTANTS AND DETERGENTS
ISSN journal
10973958 → ACNP
Volume
4
Issue
2
Year of publication
2001
Pages
163 - 166
Database
ISI
SICI code
1097-3958(200104)4:2<163:SSOOG>2.0.ZU;2-B
Abstract
Simple economical syntheses in good yield of octa-, nona-, and undecaethyle ne glycols were developed based on a coupling methodology whereby monobenzy l trior tetraethylene glycols were chain-extended either by coupling them t ogether in the presence of tosyl chloride or through reaction with alpha,om ega -ditosyl triethylene glycol in dioxane in the presence of powdered KOH. The alpha,omega -O-benzyl-protecting groups were removed by catalytic hydr ogenolysis.