Evaluation of haloperidol-ketamine mixture (1 : 1) anaesthesia in dogs

Four clinically healthy dogs of either sex, aged 3-5 years, weighing betwee n 9 and 18 kg and maintained under uniform management conditions, were admi nistered haloperidol (5 mg/ml) and ketamine (50 mg/ml) intravenously in 1:1 ratio until the pedal reflex was lost. The calculated doses of haloperidol and ketamine were 1.71 and 17.05 mg/kg body weight intravenously, respecti vely. Corneal and palpebral reflexes were maintained although pain reflexes were absent up to 20 min of the cocktail administration. The induction of anaesthesia was quick and smooth. There was moderate to good muscle relaxat ion and analgesia. Mean arterial and central venous pressures and tidal vol ume decreased significantly (P < 0.05) from baseline values. Significant ta chycardia and hyperglycemia were observed.