K. Barrett et al., Tophaceous coot of the spine mimicking epidural infection: Case report andreview of the literature, NEUROSURGER, 48(5), 2001, pp. 1170-1172
OBJECTIVE AND IMPORTANCE: Tophaceous gout uncommonly affects the axial skel
eton. The clinical presentations of gout of the spine range from back pain
to quadriplegia. Gout that presents as back pain and fever may be difficult
to distinguish from spinal infection. We present a case of a patient with
tophaceous gout of the lumbar spine who was initially diagnosed with and tr
eated for an epidural infection. The clinical and diagnostic features of to
phaceous gout of the spine are reviewed.
CLINICAL PRESENTATION: A 70-year-old man presented with a 2-day history of
fever and back pain. A physical examination revealed that he had flank tend
erness and evidence of polyarthritis affecting the elbows, knees, and right
first metatarsophalangeal joint. A magnetic resonance imaging scan of the
patient's lumbar spine showed an extensive area of abnormal gadolinium enha
ncement of the paramedian posterior soft tissues from L3 to S1 with an area
of focal enhancement extending into the right L4-L5 facet joint.
INTERVENTION: A laminectomy was performed at L4-L5, and a chalky white mate
rial in the facet joint was found eroding into the adjacent pars intra-arti
cularis. Light and polarizing microscopy confirmed the presence of gouty to
phus. No evidence of infection was found.
CONCLUSION: Gouty arthritis of the spine is rare. Thirty-seven previous cas
es have been reported. When the clinical presentation includes acute back p
ain and fever, differentiation of spinal gout from spinal infection may be
difficult. The clinical suspicion of spinal gout may lead to the correct di
agnosis by a less invasive approach than exploration and laminectomy.