Foot lesions are common and serious complications in patients with dia
betes mellitus, In recent years, several authors have, in addition to
the medical aspects, focused on the high costs for treatment of this c
omplication, However, few studies have performed a complete health-eco
nomic comparison and analysis of different treatments, This is probabl
y related to the complexity of the problem and ethical difficulties in
performing randomised clinical trials on these patients. Despite the
lack of comparative health-economic studies, most authors conclude tha
t amputations should be avoided if there is any possibility of saving
the limb, This is not only because of the economic consequences - high
costs for repeated hospitalisations. rehabilitation, horne care and s
ocial-service support associated with amputations, but also the qualit
y-of-life aspects, Alternative treatment options might seem costly in
the short term, but most cost-effectiveness analyses that also conside
r the long term perspective have concluded that treatment alternatives
in which the limb is saved are more cost effective,Methodological asp
ects, such as the perspective of a study, may cause difficulties in co
mparing results between countries and settings. By using the societal
perspective in economic studies, incentives to push costs from one sec
tor to another might be avoided.