House dust mite (HDM) allergens are the most important triggers for at
opic dermatitis. Reducing exposure to these allergens may alleviate cl
inical symptoms. Chemicals with acaricidal activity have been used to
treat upholstered furniture, carpets and bedding with the aim to reduc
e HDM allergen exposure. These chemicals, by reducing HDM, can decreas
e the concentration of mite allergens in dust but improvements in clin
ical symptoms are not always apparent, Clinical improvement is more li
kely to occur if bedding has been treated rather than carpets and upho
lstery. Future control strategies should be aimed at treating bedding,
Permethrin is a very efficient killer of mites. It is used topically
to treat scabies and head lice and is impregnated in bed nets to preve
nt mosquito bites. Even when applied to the skin in high concentration
s, it has a very low toxicity in humans and other mammals. Permethrin-
impregnated bedding may prove to be the best control method in the tre
atment of HDM allergen-triggered atopic conditions.