A novel and efficient methodology for the C-C bond forming radical cyclization of hydrophobic substrates in water

Authors
Kita, Y Nambu, H Ramesh, NG Anilkumar, G Matsugi, M
Citation
Y. Kita et al., A novel and efficient methodology for the C-C bond forming radical cyclization of hydrophobic substrates in water, ORG LETT, 3(8), 2001, pp. 1157-1160
Citations number
29
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
3
Issue
8
Year of publication
2001
Pages
1157 - 1160
Database
ISI
SICI code
1523-7060(20010419)3:8<1157:ANAEMF>2.0.ZU;2-Q
Abstract
The combination of water-soluble radical initiator 2,2' azobis[2-(2-imidazo lin-2-yl)propane] (VA-061), water soluble chain carrier 1-ethylpiperidine h ypophosphite (EPHP), and surfactant cetyltrimethylammonium bromide (CTAB) w as found to be the most suitable condition for effective radical cyclizatio n in water for a variety of hydrophobic substrates.